Look for an accredited program. Not all online degree programs are accredited and this is an important factor when you are working toward a degree.
Check if the school is totally online. Some online degree programs are not 100% online. You may have to attend some classes on campus or have some lessons sent through the mail. Therefore, you need to carefully investigate to see if the one you are interested in is totally online.
Find out the cost for getting your online degree program. You need to know if the program qualifies for low-interest financial options. If your employer offers tuition reimbursement, check whether this online degree program qualifies.
Find out the indentity of your instructors and research them online. Use a search engine to find out what they've published, where they've been quoted and how much expertise they bring to their field.
Examine the graduation program. Get a timetable so that you know how long it should take you to complete the program and when you should graduate before you start the program. You also must know which courses to take and how many credits you need to graduate.
Resources: How to Select an Online Degree | eHow.com